科研情况简介

主要从事虫媒病毒与人兽共患寄生虫流行病学与病原生物学研究。近年来先后主持国家、省、市等各类科研项目12项。发表期刊学术论文100余篇，获省部级科研奖励6项。

社会任职

中国畜牧兽医学会兽医寄生虫学分会常务理事

研究方向

虫媒病毒流行病学及病原生物学。

学术论著

1. Wang ZD, Wang B, Wei F, Han SZ, Zhang L, Yang ZT, Yan Y, Lv XL, Li L, Wang SC, Song MX, Zhang HJ, Huang SJ, Chen J, Huang FQ, Li S, Liu HH, Hong J, Jin YL, Wang W, Zhou JY, Liu Q. A New Segmented Virus Associated with Human Febrile Illness in China. N Engl J Med. 2019 May 30;380(22):2116-2125. doi: 10.1056/NEJMoa1805068. PMID: 31141633.

2. Zhao Y, Sui L, Wu P, Wang W, Wang Z, Yu Y, Hou Z, Tan G, Liu Q, Wang G. A dual-role of SARS-CoV-2 nucleocapsid protein in regulating innate immune response. Signal Transduct Target Ther. 2021 Sep 1;6(1):331. doi: 10.1038/s41392-021-00742-w. PMID: 34471099; PMCID: PMC8409078. 

3. Ma J, Lv XL, Zhang X, Han SZ, Wang ZD, Li L, Sun HT, Ma LX, Cheng ZL, Shao JW, Chen C, Zhao YH, Sui L, Liu LN, Qian J, Wang W, Liu Q. Identification of a new orthonairovirus associated with human febrile illness in China. Nat Med. 2021 Mar;27(3):434-439. doi: 10.1038/s41591-020-01228-y.

4. Du S, Peng R, Xu W, Qu X, Wang Y, Wang J, Li L, Tian M, Guan Y, Wang J, Wang G, Li H, Deng L, Shi X, Ma Y, Liu F, Sun M, Wei Z, Jin N, Liu W, Qi J, Liu Q, Liao M, Li C. Cryo-EM structure of severe fever with thrombocytopenia syndrome virus. Nat Commun. 2023 Oct 10;14(1):6333. doi: 10.1038/s41467-023-41804-7. PMID: 37816705; PMCID: PMC10564799.

5. Liu Q, Wang H, Zhang H, Sui L, Li L, Xu W, Du S, Hao P, Jiang Y, Chen J, Qu X, Tian M, Zhao Y, Guo X, Wang X, Song W, Song G, Wei Z, Hou Z, Wang G, Sun M, Li X, Lu H, Zhuang X, Jin N, Zhao Y, Li C, Liao M. The global succinylation of SARS-CoV-2-infected host cells reveals drug targets. Proc Natl Acad Sci U S A. 2022 Jul 26;119(30):e2123065119. doi: 10.1073/pnas.2123065119. Epub 2022 Jul 12. PMID: 35858407; PMCID: PMC9335334.

6. Sui L, Li L, Zhao Y, Zhao Y, Hao P, Guo X, Wang W, Wang G, Li C, Liu Q. Host cell cycle checkpoint as antiviral target for SARS-CoV-2 revealed by integrative transcriptome and proteome analyses. Signal Transduct Target Ther. 2023 Jan 3;8(1):21. doi: 10.1038/s41392-022-01296-1. PMID: 36596760; PMCID: PMC9808731.

7. Chen H, Lin S, Yang F, Chen Z, Guo L, Yang J, Lin X, Wang L, Duan Y, Wen A, Zhang X, Dai Y, Yin K, Yuan X, Yu C, He Y, He B, Cao Y, Dong H, Li J, Zhao Q, Liu Q, Lu G. Structural and functional basis of low-affinity SAM/SAH-binding in the conserved MTase of the multi-segmented Alongshan virus distantly related to canonical unsegmented flaviviruses. PLoS Pathog. 2023 Oct 13;19(10):e1011694. doi: 10.1371/journal.ppat.1011694. PMID: 37831643; PMCID: PMC10575543.

8. Liu X, Zhang X, Wang Z, Dong Z, Xie S, Jiang M, Song R, Ma J, Chen S, Chen K, Zhang H, Si X, Li C, Jin N, Wang Y, Liu Q. A Tentative Tamdy Orthonairovirus Related to Febrile Illness in Northwestern China. Clin Infect Dis. 2020 May 6;70(10):2155-2160. doi: 10.1093/cid/ciz602. PMID: 31260510.

9. Zhao Y, Sui L, Wu P, Li L, Liu L, Ma B, Wang W, Chi H, Wang Z-D, Wei Z, Hou Z, Zhang K, Niu J, Jin N, Li C, Zhao J, Wang G, Liu Q. EGR1 functions as a new host restriction factor for SARS-CoV-2 to inhibit virus replication through the E3 ubiquitin ligase MARCH8. J Virol. 2023 Oct 31;97(10):e0102823. doi: 10.1128/jvi.01028-23. Epub 2023 Sep 29. PMID: 37772822; PMCID: PMC10653994.

10. Liu Z, Li L, Xu W, Yuan Y, Liang X, Zhang L, Wei Z, Sui L, Zhao Y, Cui Y, Yin Q, Li D, Li Q, Hou Z, Wei F, Liu Q, Wang Z. Extensive diversity of RNA viruses in ticks revealed by metagenomics in northeastern China. PLoS Negl Trop Dis. 2022 Dec 21;16(12):e0011017. doi: 10.1371/journal.pntd.0011017. PMID: 36542659; PMCID: PMC9836300.

11. Sui L, Zhao Y, Wang W, Chi H, Tian T, Wu P, Zhang J, Zhao Y, Wei ZK, Hou Z, Zhou G, Wang G, Wang Z, Liu Q. Flavivirus prM interacts with MDA5 and MAVS to inhibit RLR antiviral signaling. Cell Biosci. 2023 Jan 13;13(1):9. doi: 10.1186/s13578-023-00957-0. PMID: 36639652; PMCID: PMC9837762.

12. Ma J, Yuan Y, Shao J, Sun M, He W, Chen J, Liu Q. Genomic characterization of lumpy skin disease virus in southern China. Transbound Emerg Dis. 2022 Sep;69(5):2788-2799. doi: 10.1111/tbed.14432. Epub 2022 Feb 25. PMID: 34927369. 

13. Wang YC, Wei Z, Lv X, Han S, Wang Z, Fan C, Zhang X, Shao J, Zhao YH, Sui L, Chen C, Liao M, Wang B, Jin N, Li C, Ma J, Hou ZJ, Yang Z, Han Z, Zhang Y, Niu J, Wang W, Wang Y, Liu Q. A new nairo-like virus associated with human febrile illness in China. Emerg Microbes Infect. 2021 Dec;10(1):1200-1208. doi: 10.1080/22221751.2021.1936197. PMID: 34044749; PMCID: PMC8212832.

14. Dong Z, Yang M, Wang Z, Zhao S, Xie S, Yang Y, Liu G, Zhao S, Xie J, Liu Q, Wang Y. Human Tacheng Tick Virus 2 Infection, China, 2019. Emerg Infect Dis. 2021 Feb;27(2):594-598. doi: 10.3201/eid2702.191486. PMID: 33496245; PMCID: PMC7853585.

15. Liu Q, Li MW, Wang ZD, Zhao GH, Zhu XQ. Human sparganosis, a neglected food borne zoonosis. Lancet Infect Dis. 2015 Oct;15(10):1226-1235. doi: 10.1016/S1473-3099(15)00133-4. Epub 2015 Sep 9. PMID: 26364132.

16. Liu Q, He B, Huang SY, Wei F, Zhu XQ. Severe fever with thrombocytopenia syndrome, an emerging tick-borne zoonosis. Lancet Infect Dis. 2014 Aug;14(8):763-772. doi: 10.1016/S1473-3099(14)70718-2. Epub 2014 May 15. PMID: 24837566.