- 姓名：张秀娟
- 职称：副研究员
- 联系方式：
- 导师类型：
- 所属中心：野生动物疫病与免疫学研究中心
科研情况简介
主要从事鲟鱼性别决定和分化的遗传调控机制以及鲟鱼早期性别鉴定的分子标记技术开发研究。主持国家自然科学基金项目1项，广东省自然科学基金项目2项，广东省科学院百名青年人才培养专项1项，广东省科学院野外台站项目1项，作为核心成员参加国家重点十二五重大专项、广东省自然科学基金、广东省科技计划和广州市科技计划等10多项科研项目；获得广东省科学技术进步奖励二等奖1项；发表学术论文30余篇（其中SCI收录21篇）；申请国家发明专利7项（授权2项），申请国际发明专利2项（受理）。
研究方向
性别分化基因的表达调控；非编码RNA在鲟鱼性别分化的作用及调控机制；性腺生殖细胞的体外增殖培养与分化。
学术论著
1、Zhang XJ, Zhou JB, Li LM, Huang WZ, Li HM, Jiang HY, Chen JP. Full-length transcriptome sequencing and comparative transcriptomic analysis to uncover genes involved in early gametogenesis in the gonads of Amur sturgeon (Acipenser schrenckii), Frontiers in zoology, 2020, 17: 11.
2、 Li HM, Yang BZ, Zhang XJ, Jiang HY, Li LM, Ahmad HI, Chen JP. Transcriptome analysis reveals the genetics basis underlying the development of skin appendages and immunity in hedgehog (Atelerix albiventris), Scientific Reports, 2020, 10:13920.
3、Ahmad HI, Zhou JB, Afzal G, Jiang HY, Zhang XJ, Li LM, Li HM, Liu P, Chen JP. Adaptive selection in the evolution of programmed cell death-1 and its ligands in vertebrates, Aging, 2020,12(4):3516-3557
4、 Li HM, Ping Liu, Zhang XJ, Li LM, Jiang HY, Yan H, Hou FH, Chen JP. Combined proteomics and transcriptomics reveal the genetics basis underlying the differentiation of skin appendages and immunity in pangolin, Scientific Reports, 2020, 10:14566.
5、Zhang XJ, Li GY, Jiang HY, Li LM, Ma JE, Li HM, Chen JP. Full-length transcriptome analysis of Litopenaeus vannamei reveals transcript variants involved in the innate immune system, Fish and Shellfish Immunology, 2019, 87: 346-359.
6、Jiang HY, Zhang XJ, Li LM, Ma JE, He N, Liu HY, Han RC, Chen JP. Identification of Austwickia chelonae as cause of cutaneous granuloma in endangered crocodile lizards using metataxonomics, PeerJ, 2019,7:e6574.
7、Yuan LH, Li LM, Zhang XJ, Jiang HY, Chen JP. Identification and differential expression of piRNAs in the gonads of Amur sturgeon (Acipenser schrenckii), PeerJ, 2019,7:e6709.
8、Li J, Jiang HY, Li LM, Zhang XJ, Chen JP. The effect of disease and season to hepatopancreas and intestinal mysobiota of Litopenaeus vannamei, Frontiers in microbiology, 2019,10:889.
9、Ma JE, Jiang HY, Li LM, Zhang XJ, Li HM, Li GY, Chen JP. SMRT sequencing of the full-length transcriptome of the Sunda pangolin (Manis javanica), Gene, 2019, 692:208-216.
10、Zhang XJ, Li LM, Jiang HY, Ma JE, Li J, Chen JP. Identification and differential expression of microRNAs in testis and ovary of Amur sturgeon (Acipenser schrenckii) , Gene, 2018,658:36-46.
11、Ma JE, Li LM, Jiang HY, Zhang XJ, Li J, Li GY, Chen JP. Acidic mammalian chitinase gene is highly expressed in the special oxyntic glands of Manis javanica，FEBS Open Bio, 2018, 8(8):1247-1255.
12、Jiang HY, Ma JE, Li J, Zhang XJ, Li L, He N, Liu HY, Luo SY, Han RC, Chen JP. Diets alter the gut microbiome of Crocodile Lizards, Frontiers in Microbiology, 2017, 8: 2073.
13、Ma JE, Li LM, Jiang HY, Zhang XJ, Li J, Li GY, Yuan LH, Wu J, Chen JP. Transcriptomic analysis identifies genes and pathways related to myrmecophagy in the Malayan pangolin (Manis javanica), Peer J, 2017, 5: e4140.
14、Jiang HY, Li J, Li LM, Zhang XJ, Yuan LH, Chen JP. Selective evolution of Toll-like receptor 3, 7, 8, and 9 in bats, Immunogenetics, 2017,69(4):271-285
15、Zhang XJ, Yuan LH, Li LM, Zhang HY, Chen JP. Conservatin, sex-biased expression and functional annotation of microRNAs in the gonad of Amur sturgeon (Acipenser schrenckii), Comparative Biochemistry and Physiology, Part D, 2016, 18:54-61.
16、Zhang XJ, Zhang HY, Li LM, Yuan LH, Chen JP. Transcriptome analysis and de novo annotation of the critically endangered Amur sturgeon (Acipenser schrenckii), Genetics and molecular research, 2016,15(2): 15027999.
17、Zhang XJ, Li L, Bai YS, Shi RY, Wei HX, Zhang SQ, Mouse undifferentiated spermatogonial stem cells cultured as aggregates under simulated microgravity, Andrologia, 2014, 46(9), 1013-1021.
18、Yuan LH#, Zhang XJ#(共同一作), Li LM, Jiang HY, Chen JP. High-throughput sequencing of microRNA transcriptome and expression assay in the sturgeon, Acipenser schrenckii, PloS ONE, 2014, 9(12): e115251.
19、 Jiang HY, Chen W, Su L, Su Q, Li GY, Ahmad HI, Li LM, Zhang XJ, Li HM, Chen JP. Impact of host intraspecies genetic variation, diet, and age on bacterial and fungal intestinal microbiota in tigers, MicrobiologyOpen, 2020, 9(7):e1050.
20、Shi RY, Bai YS, Li SP, Wei HX, Zhang XJ, Li L, Tian XC, Jiang QY, Zhang SQ. Characteristics of spermatogonial stem cells derived from neonatal porcine testis, Andrologia, 2015, 47(7):765-778.
21、 Li LM, Wei L, Jiang HY, Zhang Y, Zhang XJ, Chen JP. Rapid development of 12 polymorphic microsatellite markers for the Amur sturgeon (Acipenser schrenckii) using next generation sequencing technology, Genetics and molecular research, 2015, 14(3):7910-7913.
发明专利
1、张秀娟，陈金平，吴文化，周佳滨，李林妙，江海英.国家发明专利：鉴定鲟鱼性别的microRNA血清标志物、引物组、试剂盒及其应用. 专利号：ZL202010314533.2；授权公告日：2020.07.24.
2、张秀娟，陈金平，白银山，张守全，王承民. 国家发明专利：一种利用FACTIII微载体体外扩增精原干细胞的三维动态培养方法. 专利号：ZL202010314524.3；授权公告日：2020.07.31.
科技奖项
1、广东省科学技术奖二等奖：我国鲟鱼资源评价、性腺发育研究及应用，授奖时间：2018.02，排名：第七。
联系我们
电话：
信箱：giz@giz.gd.cn
地址：广东省科学院动物研究所